Catalog Number :BGK9QYH9

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LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF-κB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.

The BioGems Murine Light Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure Light with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for Light. It contains NS0-expressed recombinant Light. The detection antibody is a biotinylated goat polyclonal antibody specific for Light. The kit is analytically validated with ready to use reagents.

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LIGHT屬于TNF配體家族，并且可以通過皰疹病毒進(jìn)入介質(zhì)A型受體（HVEM，TNFRSF14），LTβR或與decoy受體DcR3結(jié)合而傳導(dǎo)信號。它在脾細(xì)胞，活化PBL，CD8 +腫瘤浸潤淋巴細(xì)胞，粒細(xì)胞和單核細(xì)胞中表達(dá)。LIGHT可以活化NF-κB以共刺激淋巴細(xì)胞的活化并誘導(dǎo)某些人類腫瘤細(xì)胞的凋亡。

BioGems鼠Light預(yù)包被ELISA試劑盒是一種固相免疫分析試劑，專門設(shè)計(jì)用于檢測Light，并在96孔微孔板上預(yù)包被Light特異性小鼠單克隆抗體。 它含有NS0表達(dá)的重組Light。 檢測抗體是對Light特異的生物素化山羊多克隆抗體。該試劑盒經(jīng)過分析驗(yàn)證，是即用型試劑。

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Product Details

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Components組份

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Reproducibility可重復(fù)性